In a study of mouse and human genes, scientists pinpointed 145 genes that regulate the cartilage cells in kid's growth plates and could determine how tall they grow.
Scientists have pinpointed 145 potential"height genes" in cells that make up the cartilage at the ends of children's bones and affect how tall they grow.
In a study published Friday in the journal Cell Genomics , Renthal and her colleagues screened 600 million mouse cartilage cells to find genes that influence how the cells proliferate and mature. They used CRISPR genome-editing technology to"knock out" candidate genes, which allowed the researchers to observe what happened when these genes were erased and no longer regulated cartilage cells.
The comparison revealed a remarkable overlap between genetic"hotpots" linked to human height in the GWAS and the 145 genes that control cartilage cell growth in mice. This means that these genes, which the researchers have now precisely located in the human genome, could influence height more than other genetic factors do.
Brasil Últimas Notícias, Brasil Manchetes
Similar News:Você também pode ler notícias semelhantes a esta que coletamos de outras fontes de notícias.
Brush fire scorches nearly 4,000 acres in Manchester Township, N.J., threatens nearly 150 structures; Other fires now under control in Teaneck, Jersey CityCrews are working to get a handle on a large wildfire which has scorched nearly 4,000 acres so far in Manchester Township, N.J. csloantv reports.
Consulte Mais informação »
Theme park brawl involving up to 150 teens injures off-duty deputyA Missouri sheriff’s office says up to 150 teenagers were involved in a fight at an amusement park over the weekend.
Consulte Mais informação »
Yandel & Feid’s ‘Yandel 150’ Reaches No. 1 on Latin Airplay & Latin Rhythm Airplay Charts.Yandel & ferxxo4;s :Yandel 150' hits No.1. on the Latin Airplay & Latin Rhythm Airplay charts.
Consulte Mais informação »
Homeward bound: Lost dog returns home after surviving epic 150-mile journey across Alaskan sea iceNanuq, a 1-year-old Australian shepherd, went missing in Savoonga, a St. Lawrence Island community in the Bering Strait, and was found weeks later in the Alaskan city of Wales, despite roughly 150 miles of sea between the two locations.
Consulte Mais informação »
Missing dog walks 150 miles across Alaskan sea ice, survives 'really big bite' by unknown animalA 1-year-old Australian shepherd took an epic trek across 150 miles of frozen Bering Sea ice that included being bitten by a seal or polar bear before he was safely returned to his home in Alaska.
Consulte Mais informação »
Alaska Family’s Lost Dog Found After 150-Mile Journey Across Frozen Sea“I was like, ‘No freakin’ way! That’s our dog! What is he doing in Wales?’” Nanuq’s owner, Mandy Iworrigan, said.
Consulte Mais informação »