Abnormally high blood sugar (glucose) levels can result in type 2 diabetes when things go awry with the body's skeletal muscle, which plays a key role in regulating glucose.
Biophysics Reviews
"We can use skeletal muscle grown within the lab to capture and study diabetes disease characteristics," said co-author Christina Sheng."Moreover, these so-called in vitro models enable researchers to discover new medicines for diabetes.
To mimic diabetes, the researchers treat lab-grown skeletal muscle with excess sugar, insulin, fats, or cells that promote inflammation and study how these factors affect skeletal muscle health.
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