The race to eradicate HIV is picking up with the help of mRNA technology. 💉 engineering
The biotechnology company has collaborated with the nonprofit International AIDS Vaccine Initiative to develop the vaccine in the wake of the success of mRNA technology, which shaved years off typical vaccine development times and allowed for the emerging of COVID-19 vaccines in record time.Modern's goal with this vaccine is to stimulate the production of a type of antibody known as"broadly neutralizing antibodies," or bnAbs.
During the Phase 1 trial, which is being carried out in the United States among 56 HIV-negative healthy adults, participants will be injected with an immunogen, which is a substance that can trigger an immune response, followed by a booster immunogen later. "Further immunogens will be needed to guide the immune system on this path, but this prime-boost combination could be the first key element of an eventual HIV immunization regimen," explained David Diemert, a lead investigator at one of the four sites where the trial is being carried out.
To kick off the trial, the first participants were given doses at George Washington University School of Medicine and Health Sciences in Washington, D.C. After receiving their final dose, the participants will be monitored for the safety and efficacy of the new vaccine for up to six months.
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