New hypothesis unifies several contrasting theories that may help explain the underlying cause of IBS. According to a new theory from researchers out of Cedars-Sinai Medical Center, gravity may be the cause of irritable bowel syndrome (IBS), the most common gastrointestinal disorder. Brennan S
According to a new study from Cedars-Sinai Medical Center, irritable bowel syndrome may be caused by gravity.
Brennan Spiegel, MD, MSHS, director of Health Services Research at Cedars-Sinai and author of the hypothesis, explains that IBS—and many other conditions—could result from the body’s inability to manage gravity.gravity has relentlessly shaped everything on the planet,” said Spiegel, who is also a professor of Medicine. “Our bodies are affected by gravity from the moment we’re born to the day we die. It’s a force so fundamental that we rarely note its constant influence on our health.
The underlying mechanism of IBS has been puzzling researchers since it was first described over a century ago. While the disorder affects up to 10% of the world’s population, experts still aren’t sure exactly how or why it develops. “There’s such a variety of explanations that I wondered if they could all be simultaneously true,” said Spiegel. “As I thought about each theory, from those involving motility, to bacteria, to the neuropsychology of IBS, I realized they might all point back to gravity as a unifying factor. It seemed pretty strange at first, no doubt, but as I developed the idea and ran it by colleagues, it started to make sense.
“The body evolved to hoist this load with a set of support structures. If these systems fail, then IBS symptoms can occur along with musculoskeletal problems,” Spiegel said. Some people are more resilient to G-forces than others. For example, one person may raise their hands and grin while dropping on a roller coaster while another grits their teeth and groans. The first person is amused while the second feels threatened, revealing a spectrum of what Spiegel calls “G-force vigilance.”
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