Researchers reconstructed gut bacterial genomes.
By Pooja Toshniwal PahariaAug 21 2023Reviewed by Lily Ramsey, LLM In a recent study posted to the medRxiv* preprint server, researchers reconstructed gut bacterial genomes.
*Important notice: medRxiv publishes preliminary scientific reports that are not peer-reviewed and, therefore, should not be regarded as conclusive, guide clinical practice/health-related behavior, or treated as established information. About the study In the present study, researchers comparatively evaluated the change in weight following MDCF-2 treatment versus the conventional and more calorie-dense RUSF treatment among MAM children.
Polymerase chain reaction amplicons generated from bacterial 16S ribosomal ribonucleic acid genes in fecal biological specimens were sequenced. Taxonomy was assigned to MAGs using Genome Taxonomy Database data. Linear mixed effects modeling was performed to identify MAGs with abundances significantly related to weight gain.
Related StoriesThe gene set enrichment analysis findings showed that MAGs whose abundances increased faster in the MDCF-2 compared to the RUSF group were significantly enriched for those positively associated with WLZ.
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