MetroHealth opens new facility for cell-based cancer therapies

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MetroHealth opens new facility for cell-based cancer therapies
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MetroHealth has completed construction on a facility for the development of cancer therapies derived from a patient’s own immune cells. The A new lab is designed to speed and improve cancer treatment.

facility for the development of cancer therapies derived from a patient’s own immune cells.

In both of these therapies a patient’s own immune cells are collected, modified in the laboratory to recognize cancer cells, and then returned to the patient. CAR-T is primarily effective for certain blood-based cancers, while TIL is being developed for certain types of solid tumors. The benefits of hospital-based lab capabilities have led a number of systems to invest in their own laboratories.recently spent $10 million

Currently, even centers that are producing their own CAR-T cells still rely on commercially available products called vectors to “educate” the cells against cancer. These commercial products are the building blocks of all cellular therapies, and they are in extremely short supply, explained MetroHealth Service Line Administrator for Cancer CareTheir lack of availability creates a bottleneck that impedes a lab’s ability to produce clinical treatments in a timely manner.

“What we’re doing here at MetroHealth is investing in something that can help fuel the discovery of more of these CAR-T’s ... and at the same time we will also have the ability to build those CAR-T cells, so we can take our own input and say hey collaborator in Boston, or collaborator in New York, or anywhere, you have a CAR-T product that you want to develop? we’ll do it from beginning to end,” said Kovach.

Although cell-based immune therapies like CAR-T received FDA approval several years ago, the field as a whole is still rather new, and rapidly changing. This type of leading-edge research is most often offered at large centers of academic research, rather than public hospitals.

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