The number of drug overdose deaths involving a powerful animal tranquilizer called xylazine has skyrocketed in recent years, according to the CDC. The tranquilizer has been increasingly found laced in the illegal supply of fentanyl.
Using death certificates dating back to 2018, researchers found the rate of drug overdose deaths involving xylazine increased from .03 per 100,000 people to 1.06 per 100,000 people in 2021.
Despite the increased detection of xylazine in overdoses, there is no evidence that tranq increases the risk of death, although the mixture of xylazine and fentanyl can lead to worsening withdrawal symptoms.State Unintentional Drug Overdose Reporting System "Xylazine doesn't cause as much suppression of breathing as fentanyl does," said Perrone, who was not involved with the new research."While it might not cause as many fatalities, we're still really worried about the growing xylazine presence in the drug supply," Perrone said."There is a lot of tissue loss," Perrone said."There is a crater where their skin used to be, and it's easily infected.
"What we want naloxone to do is restore breathing, and it still works to restore breathing very effectively, even in the presence of xylazine," Perrone said."It may not wake the patient up because they may still be sleepy from their xylazine, but that is actually fine. We can get the patient to the hospital safely."
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