A Science analysis of the cryogenic electron microscopy structures of the full-length spike trimers of the Delta, Kappa and Gamma variants of SARSCoV2 has identified properties that might account for the Delta variant's heightened transmissibility.
). The three strains studied here show once again how different variants can use different strategies to remodel their NTD and evade host immunity. One notable implication is that the NTD function does not require specific structural elements or sequences because the surface loops, β strands in the core structure, and even some N-linked glycans can be rearranged in different ways without compromising viral infectivity.
. This license does not apply to figures/photos/artwork or other content included in the article that is credited to a third party; obtain authorization from the rights holder before using such material.
Brasil Últimas Notícias, Brasil Manchetes
Similar News:Você também pode ler notícias semelhantes a esta que coletamos de outras fontes de notícias.
SARS-CoV-2 infection in free-ranging white-tailed deer - NatureNature - <ArticleTitle Language="En" xml:lang="en">SARS-CoV-2 infection in free-ranging white-tailed deer</ArticleTitle>
Consulte Mais informação »
An oral SARS-CoV-2 Mpro inhibitor clinical candidate for the treatment of COVID-19A new Science study details PF-07321332, an orally active, small-molecule inhibitor of the SARSCoV2 main protease, a key viral target. In a phase I clinical trial, it achieved concentrations expected to inhibit the virus based on in vitro studies. pfizer
Consulte Mais informação »
Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodiesNature research paper: Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies
Consulte Mais informação »
Broadly neutralizing antibodies overcome SARS-CoV-2 Omicron antigenic shiftNature research paper: Broadly neutralizing antibodies overcome SARS-CoV-2 Omicron antigenic shift
Consulte Mais informação »
Pregnancy influences immune responses to SARS-CoV-2Pregnancy and fetal sex influence the quality of antibody responses to SARSCoV2 infection and immunization, argues a new ScienceTM Focus article. Read more:
Consulte Mais informação »
Allelic variation in class I HLA determines CD8+ T cell repertoire shape and cross-reactive memory responses to SARS-CoV-2Studying ~56 million T cells from 55 COVID patients, researchers in SciImmunology offer a high-res picture of epitope reactivity and TCR usage in CD8 T cells specific for SARSCoV2, some of which also react to “common cold” coronaviruses.
Consulte Mais informação »