Although the COVID-19 pandemic was the first time most of humanity learned of the now infamous disease, the family of coronaviruses was first identified in the mid-1960s. In a new study, molecular biologist Steven Van Doren, a scientist in the University of Missouri College of Agriculture, Food and Natural Resources, has uncovered unexpected actions of a key player in how the coronavirus infects its target—a discovery that could guide further vaccine development.
could further inform why the fusion peptide may be an important target for vaccine development capable of fighting all types of coronavirus infections.
Another potential application of this research could be to create a novel strategy to penetrate cells. "There may be many strategies for crossing membranes, but it's conceivable that the fusion peptide work could help further development of more ways to cross cellular membranes, which could be useful to deliver therapeutics through cell membranes," Van Doren said.
Further, this research broadens understanding of protein insertion in membranes, which has broader relevance to the scientific community.look like and what they can do," Van Doren said."I got fascinated by the science when I was still a teenager, and it's intriguing to me the things they can do, so studying how proteins work has been something that has stuck with me for decades now—I'd say going on almost 40 years.
The study"SARS-CoV-2 Fusion Peptide Sculpting of a Membrane with Insertion of Charged and Polar Groups" is published inSteven R. Van Doren et al, SARS-CoV-2 fusion peptide sculpting of a membrane with insertion of charged and polar groups,
Brasil Últimas Notícias, Brasil Manchetes
Similar News:Você também pode ler notícias semelhantes a esta que coletamos de outras fontes de notícias.
Inhalable molecules neutralize SARS-CoV-2 in miceNanofitins, which are derived from a protein found in Sulfolobus acidocaldarius—an archaeal microorganism found in hot springs—successfully neutralized SARS-CoV-2 in mice and were well-tolerated. When inhaled by the rodents, the engineered nanofitins, which inhibit the virus by binding to its spike proteins, were observed to quickly reach the lungs in high doses both preventing and clearing early infections, researchers from biotech company Affilogic report Aug. 30 in the journal Molecular Therapy.
Consulte Mais informação »
American Airlines flight attendants vote to authorize a strike, although a walkout still unlikelyFlight attendants at American Airlines say they are willing to strike as negotiations for pay raises drag on.
Consulte Mais informação »
American Airlines flight attendants vote to authorize a strike, although a walkout still unlikelyFlight attendants at American Airlines say they are willing to strike as negotiations for pay raises drag on
Consulte Mais informação »
American Airlines flight attendants vote to authorize a strike, although a walkout still unlikelyThe Association of Professional Flight Attendants said Wednesday that more than 99% of members who voted recently favored giving the union power to call a strike.
Consulte Mais informação »
American Airlines flight attendants vote to authorize a strike, although a walkout still unlikelyThe Association of Professional Flight Attendants said Wednesday that more than 99% of members who voted recently favored giving the union power to call a strike.
Consulte Mais informação »
American Airlines flight attendants vote to authorize a strike, although a walkout still unlikelyFlight attendants at American Airlines say they are willing to strike as negotiations for pay raises drag on.
Consulte Mais informação »