Long COVID-19 and other chronic respiratory conditions after viral infections may stem from an overactive immune response in the lungs. Shortly after the beginning of the COVID-19 pandemic, anecdotal reports emerged of previously healthy individuals that were experiencing lingering symptoms and w
A legion of immune cells work together to remove invading pathogens.
Another type of immune cell called monocytes are also involved in fighting respiratory infections, serving among the first responders by producing virus- and tissue-damaging cytokines. Research has found that these cells also in the lungs of long COVID-19 patients and promote a pro-inflammatory environment that can cause further damage.
Understanding the immunological mechanisms underlying long COVID-19 is the first step to addressing a. Identifying the subtle differences in how the same immune cells that protect you during an active infection can later become harmful could lead to earlier diagnosis of long COVID-19. Moreover, based on our findings, my team and I believe treatments that target the immune system could be an effective approach to manage long COVID-19 symptoms.
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