Is remdesivir the drug that can kill the coronavirus?

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Is remdesivir the drug that can kill the coronavirus?
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Science remains equivocal about whether remdesivir actually works for covid-19 sufferers

AN EFFECTIVE DRUG to treat covid-19 would transform the battle against the pandemic. Without one, whole countries have had to lock themselves down to limit the spread of the novel coronavirus which has infected more than 2m people and killed nearly 150,000, according to official records; the real toll is probably much greater.

This hope has energised the hunt for a drug against covid-19 since the early days of the pandemic. President Donald Trump, for one, has touted hydroxychloroquine, an anti-malarial drug. But it is remdesivir, an experimental antiviral drug, that is proving the most exciting. The share price of its maker, Gilead Sciences, shot up by 12% on April 17th after a leak in STAT, an online medical publication, of a discussion suggesting impressive results of a trial with the drug.

Yet science remains equivocal about whether this drug actually works for covid-19 sufferers. Two trials in China have already failed, because of lack of enrolment. The recent publication in the, of a study of remdesivir given to 53 severely afflicted patients, reported that 68% of them improved. However the study has proven divisive among scientists. To begin with, errors can be large given the small number of patients.

Stephen Evans, a professor of pharmacoepidemiology at the London School of Hygiene and Tropical Medicine, warns that medicine is littered with instances where treatments were incorrectly believed to have strong benefits based on non-randomised data. Luckily, there are some gold-standard trials under way. One global effort, under the auspices of the World Health Organisation, began in mid-March but results are not expected until after June.

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