People with elevated levels of protein prostasin seem to have a higher risk of developing diabetes and dying from cancer, according to a large, prospective, population-based study.
The finding may provide new insights into why people with diabetes have an increased risk of cancer.
"The relationship between diabetes and cancer is poorly understood," Engström said."To our knowledge, this is the first big population study of prostasin and risk of diabetes." During the follow-up periods of 21.9 years for diabetes and 23.5 years for cancer, on average, 702 participants developed diabetes and 651 died from cancer. Again, the analysis found a significantly higher adjusted hazard ratio for participants in the fourth quartile: about 75% higher for diabetes , and, after multivariable analysis, about 40% higher for death from cancer .
Chen pointed out that the study reported a lower range of 0.24 pg/mL and an upper range of 7,800 pg/mL.
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