Is Multiple Sclerosis Hereditary, or Do Environmental Factors Play a Role?

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Is Multiple Sclerosis Hereditary, or Do Environmental Factors Play a Role?
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Is Multiple Sclerosis Hereditary?

Multiple sclerosis is an autoimmune condition where, for reasons scientists are still trying to understand, your body’s immune system suddenly attacks the coating covering the nerves in your brain and spinal cord.

Scientists have not found one true cause behind multiple sclerosis. But what is known is that there is a genetic factor that could influence your disease risk.There are many genes—as much as—that each have their own small contribution to multiple sclerosis. “There’s a lot of research looking at what alleles, pieces of gene, in people with multiple sclerosis have that aren’t seen in the general population that could make them susceptible to the disease,” adds says.

shows that some of these genes—HLA-DRB1 and the HLA-DRB1*15:01—are involved in innate immunity, the first line of defense when a threat is present in the body, and contributes to the progression of multiple sclerosis.Having a family history of multiple sclerosis can also elevate your risk of the disease, although it’s not something that’s passed down from parent to child. What’s more, even if a relative has multiple sclerosis, Dr.

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