Inside drugmakers' strategy to boost cancer medicines with 'Lazarus effect'

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Inside drugmakers' strategy to boost cancer medicines with 'Lazarus effect'
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In the halls of MD Anderson Cancer Center, the drug Vitrakvi is known for having...

) are taking matters into their own hands, bulking up staff to increase patient and physician awareness about testing and building up a gene testing infrastructure that for many community hospitals still does not exist.

The deal adds RET mutations - the target of both Lilly’s and Blueprint’s drugs - to Thermo’s Oncomine Dx Target Test, which local pathology labs can use to identify multiple genes linked with non-small cell lung cancer. At MD Anderson, which sees 100,000 new cancer patients a year, only around 10,000 eventually have their tumors sequenced.Xin Zheng, 47, a mother of three in Michigan who was referred to Reuters by Blueprint, was diagnosed with stage 4 lung cancer in 2016. After failing several treatments, she was out of options.

Dr. David Hyman of Memorial Sloan Kettering Cancer Center, who tested Vitrakvi in clinical trials, said making these tests the norm for advanced cancer patients will require a huge shift in the way oncology is practiced.

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