Study explores activity of distinct interneuron populations in a mouse hippocampus during memoryconsolidation NatureNeuro
Spatial information for significantly tuned interneurons, broken down by both region and subtype. Immobility-active CB/SATB1- neurons were silenced during locomotion and were thus not considered in this analysis. Data from 188 cells in n = 9 mice. Significance values over individual violin plots show the results of signed-rank tests. Within-day spatial stability of all interneurons, broken down by both region and subtype. Plotted as in A.
data from 20 imaging sessions, AAC data from 22 sessions, SOM data from 14 sessions, CCK data from 9 sessions, and CB/SATB1 + data from 2 sessions; data from n = 9 mice. Data reported as mean ± s.d. Right: Same data as on the left, but for negatively tuned CA2 interneurons . Significant differences in the fraction of negatively tuned CA2 interneurons by subtype are indicated = 0.0075, p = 0.0024, p = 0.0012, p = 0.001).
data from 20 imaging sessions, AAC data from 22 sessions, SOM data from 14 sessions, CCK data from 9 sessions, and CB/SATB1 + data from 2 sessions; data from n = 9 mice. Data reported as mean ± s.d. Example of 100 seconds of real interneuron activity during locomotion and the predicted activity from a GLM. The predicted activity for each cell was calculated based on 4 predictor behavioral variables: velocity, position, licking, and water delivery .
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