In a world-first, University of Queensland researchers have successfully bred lethal cone snails in a laboratory aquarium, opening up new possibilities for drug development.
Researchers from the University of Queensland's Institute for Molecular Bioscience, namely Professor Richard Lewis, Dr. Aymeric Rogalski, and Dr. Himaya Siddhihalu Wickrama Hewage, specialize in studying venoms as potential therapeutics.
Professor Lewis elaborated on their success with venom molecules, particularly in developing pain medications. However, he emphasized that further exploration of the pharmacology of these molecules is necessary to determine their potential therapeutic applications for different disease classes.During their research, one unexpected discovery was that juvenile cone snails have a distinct feeding behavior and do not prey on fish like adult individuals of the same species.
"They jab the worm with a harpoon-like structure before injecting it with venom to subdue it. The juvenile snail then slowly stalks the worm and sucks it up, like a small piece of spaghetti."during their larvae stage. Still, their diet transforms once they metamorphose into half-millimeter-long juveniles.
He attributed this knowledge gap to difficulties locating eggs, larvae, and juveniles and raising them in an aquarium setting.
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