Trials for its use against COVID-19 continue, with some researchers still hopeful it can serve as a preventative in people not yet exposed to the virus.
"The reason I say I don't think it's a nail in the coffin is that, fortunately, they didn't find any serious adverse effects ... no one's actually being killed by hydroxychloroquine and that's what I think puts a nail in the coffin."
Medical teams tell NBC News the politicization of the drug has complicated the trial enrollment processes. "What we found in our trials was a combination of people not being interested in enrolling, a number of people withdrawing from the trials because either they were concerned or their physician was concerned — and so we ended up in our trials with very limited enrollment," Griffin explained.
As a result, said Belmont,"I fear I may have lost the ability" to demonstrate a meaningful effect of hydroxychloroquine on acquiring the infection, “but that's the reality of doing clinical science.” He still hopes to provide insight into how patients tolerate the drug and address other exploratory goals.
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