How Fecal DNA Testing can Help with Early Detection of Colorectal Cancer BGI_Genomics DNA colorectalcancer cancer screening
Sponsored Content by BGI GenomicsFeb 10 2023 Overview of the Current Colorectal Cancer Landscape Colorectal cancer is the third most common cancer worldwide, with over 1.9 million new cases in 2020, and is also the third most common cause of cancer-related mortality.1 Colorectal cancer rates are particularly high in the developed world, and alarmingly, the rates are increasing in many other countries as well, with changing dietary habits thought to be one major contributing factor.
A study published in 2021 demonstrated the tremendous economic burden that colorectal cancer could place on patients, their families, and the healthcare systems. It is estimated that the economic burden of colorectal cancer across Europe in 2015 was as high as €19.1 billion, which included the direct expenditure on cancer care and non-healthcare costs such as loss of productivity and opportunity costs for informal carers.
When colorectal cancers are detected early, they are highly treatable. If a diagnosis is made when the cancer is still highly localized, the overall five-year survival rate can be around 90%. In contrast, in metastatic colorectal cancer, the five-year survival rate decreases drastically, to only around 10%.7Current Screening Approaches for Colorectal Cancer Current colorectal cancer screening methods include invasive and non-invasive tests.
An abnormal result from fecal-based tests may indicate the presence of colorectal cancer or advanced adenoma, and should be followed by a diagnostic colonoscopy.
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