Two drug companies have developed antiviral pills to fight Covid-19. They both work by blocking enzymes that play a role in how the virus replicates in the body.
Molnupiravir and Paxlovid both aim to stop the coronavirus from replicating, but they use slightly different methods.
The so-called error catastrophe method is effective, said Katherine Seley-Radtke, a medical chemist at the University of Maryland, Baltimore County, who specializes in antiviral drug development. “These drugs can be administered at any stage of the infection based on their mode of action,” said Fenyong Liu, a virologist at the University of California, Berkeley. However, they will be more effective if they are given in the early stages of the infection, he added, “because more severe complications and damage due to infection are always associated with later stages.”
The clinical trials for both treatments reported no unfavorable side effects that were any different from those of the placebo, which experts say is promising.
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