GlaxoSmithKline and AstraZeneca will each present trial data on a promising new ...
- GlaxoSmithKline and AstraZeneca will each present trial data on a promising new class of drugs against ovarian cancer on Saturday as Britain’s top drugmakers compete to burnish their oncology credentials.
Both companies have already flagged that their respective drug candidates, part of a class known as PARP inhibitors, did well in staving off a return of ovarian cancer in women that had responded to initial standard treatment.GSK and Astra, which are also competing in respiratory drugs, have held back full trial details for the ESMO event.
Drugmakers try to use that to their advantage with PARP inhibitors that block what is left of the DNA repair mechanism so cancer cells fail to replicate and a tumor cannot sustain itself. “That becomes relevant when you start thinking about the drugs’ role in other tumor types like prostate cancer and breast cancer where the incidence of new patients each year is much greater than in ovarian cancer,” he said.
“The outcome of this trial is the key test of Hal Barron saying this will justify the deal on its own if it comes good. This would be vindication for the first big acquisition that he has done for Glaxo,” said Bowler of Schroders.
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