Lynch syndrome affects 1 in 279 individuals, or an estimated 1.1 million people in the United States.
Lynch syndrome causes about 4,300 colorectal cancers and 1,800 uterine cancers per year.
Lynch syndrome is currently the most common cause of hereditary colorectal cancer and people who inherit the condition have an estimated lifetime risk as high as 80% for developing cancerous growths, according to theAbout 1 in 279 individuals, an estimated 1.1 million people in the U.S. alone have Lynch syndrome.
Sanchez explained that patients with Lynch syndrome are born with a genetic defect in a gene that is involved in DNA repair. This means that people with Lynch syndrome are more prone than others to replicate these DNA errors over their lifetime which means an increased risk of cancer. "An infectious agent is foreign, these tumor cells are also foreign, because they are making all these novel proteins that we call neo-antigens and that is how they prime the immune system," Sanchez said.
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