Gene expression phylogenies and ancestral transcriptome reconstruction resolves major transitions in the origins of pregnancy

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Gene expression phylogenies and ancestral transcriptome reconstruction resolves major transitions in the origins of pregnancy
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Study: How placentas evolved in mammals elife

Structural and physiological changes in the female reproductive system underlie the origins of pregnancy in multiple vertebrate lineages. In mammals, the glandular portion of the lower reproductive tract has transformed into a structure specialized for supporting fetal development. These specializations range from relatively simple maternal nutrient provisioning in egg-laying monotremes to an elaborate suite of traits that support intimate maternal-fetal interactions in Eutherians.

All data generated or analysed during this study are included in the manuscript and supporting file; Source Data files have been provided for Figures 2, 3 and 5.

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