The Loose Women panellist has found the perfect occasion dress
seems to have an endless supply of gorgeous dresses, from floral maxi dresses to slinky midis – and her new find has just dropped in price by a huge 40% in the Karen Millen sale.features a figure-skimming fit with a delicately pleated skirt, and we think it would make the ultimate occasion dress for summer. If you love it you'll need to add it to your basket soon though, as it's already sold out in select sizes.
Frankie showcased the Karen Millen number as part of her weekly #FrankiesFaves, where the star shares her top fashion picks.In her most recent #FrankiesFaves, theFrankie captioned the post: "Persuaded @mrstorcook to get involved in today's faves for a sister edition. Helping her to pick some pieces for her first family holiday with 3 under 3."
Fans were quick to share their love for the high street pieces, and one follower wrote: "These are all gorgeous, beautiful ladies." Whilst another added: "Love every look! Sister sister!"ASOS is filled with satin dresses for summer, but our favourite is this sunshine yellow slip midi. We love it teamed with a pair of dad sandals.Reformation's silk floral dress is the ultimate investment for your summer wardrobe.
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Effects of intravenous administration of magnesium sulfate in propofol-based sedation for ERCP in elderly patients: a randomized, double-blind, placebo-controlled study - BMC GeriatricsBackground Propofol-based sedations are widely used in elderly patients for endoscopic retrograde cholangiopancreatography (ERCP) procedure, but respiratory depression and cardiovascular adverse events commonly occur. Magnesium administered intravenously can alleviate pain and decrease propofol requirements during surgery. We hypothesized that intravenous magnesium was used as adjuvant to propofol might be beneficial in elderly patients undergoing ERCP procedures. Methods Eighty patients aged from 65 to 79 years who were scheduled for ERCP were enrolled. All patients were intravenously administered 0.1 µg/kg sufentanil as premedication. The patients were randomized to receive either intravenous magnesium sulfate 40 mg/kg (group M, n = 40) or the same volume of normal saline (group N, n = 40) over 15 min before the start of sedation. Intraoperative sedation was provided by propofol. Total propofol requirement during ERCP was the primary outcome. Results The total propofol consumption were reduced by 21.4% in the group M compared with the group N (151.2 ± 53.3 mg vs. 192.3 ± 72.1 mg, P = 0.001). The incidences of respiratory depression episodes and involuntary movement were less in the group M than those in the group N (0/40 vs. 6/40, P = 0.011; 4/40 vs. 11/40, P = 0.045; respectively). In the group M, the patients experienced less pain than those in the group N at 30 min after the procedure (1 [0–1] vs. 2 [1–2], P | 0.001). Correspondingly, the patients’ satisfaction was clearly higher in the group M (P = 0.005). There was a tendency towards lower intraoperative heart rate and mean arterial pressure in group M. Conclusions A single bolus of 40 mg/kg of intravenous magnesium can significantly reduce propofol consumption during ERCP, with higher sedation success and lower adverse events. Trial Registration ID UMIN000044737. Registered 02/07/2021.
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