This article talks about flexible and highly efficient dry granulation.
Sponsored Content by L.B. Bohle Maschinen und Verfahren GmbHReviewed by Olivia FrostJul 31 2024 Dry granulation, also called roller compaction, has been a popular method in recent years and has many applications. The powder is compressed between revolving rollers to generate flakes. The flakes are crushed with a sieve and sieve inserts to produce granules with the correct particle size distribution.
Unlike wet granulation, a batch process, dry granulation is a well-established method of producing solids. Dry granulation is very useful for moisture-sensitive medicinal compounds. During continuous gap distance measuring, real and target values are compared. The idea is to keep a parallel gap between the rolls throughout the operation so that the departing flake has the same qualities across its entire width.The screw speed is linked to the gap adjustment via a control loop. As a result, when the nip opens, the screw moves less material into the nip, allowing it to close again. The automatic control creates flakes with preset thickness and porosity.
The BRC's unique compaction force and flake thickness management ensures uniform material compaction across a production range of < 1 - 400 kg/h. At the same time, the smart, unique machine design makes handling easier and shortens the assembly process. At the same time, each BRC may be quickly converted to an alternate rotary screen BRS, allowing it to be easily tailored to process and flake needs.
While roller compaction is a continuous production method that can accommodate both big and small batch sizes, nearly all products are produced in batches.Changeover after cleaning and reassembling takes 30 minutes. Competitors' systems require up to eight hours for cleaning and assembly. The BRC requires only the bare minimum of tools , while all other components are designed for tool-free replacement.
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