Overdose reversal drugs don't work on this tranquilizer
Travis County officials held a press conference today alerting the community that five people have died since May from drug overdoses related to xylazine, which causes overdoses Narcan can’t reverse. In all cases,, is not an opiate like fentanyl, but a sedative. It was initially studied for treating high blood pressure, but never approved for human use, Travis County Chief Medical Examinersaid.
Crucially, overdose reversal drugs like naloxone, brand name Narcan, do not work on xylazine because it’s not an opioid. “In fact, there is not any available agent to reverse the effects of xylazine,” said Pinckard. Plus, “its duration is longer, so it's thought to enhance the effect of the fentanyl and heroin that it is part of.” However, officials noted that it’s still important to use naloxone if you come upon someone you think is overdosing, and to administer CPR.
Fentanyl is already 50 times stronger than heroin, and has increased Travis County’s accidental overdose deaths more than tenfold between 2019-2022. Fentanyl went from being involved in 12% of drug deaths in 2019 to 59% in 2022, and in 2022,. The vast majority of overdose deaths involve multiple drugs, noted Pickard – the five that involved xylazine this summer included other recreational drugs like methamphetamine, cocaine, and mirtazapine.
“We're here today to particularly speak to those in our community who are living with substance use disorder, and ask them to not use by themselves,” said Health Authority Dr.
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