'Extinct' Coronaviruses Still Thrive in North America, Just Not in Humans

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'Extinct' Coronaviruses Still Thrive in North America, Just Not in Humans
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Variations in the SARS-CoV-2 virus that have not been detected in human beings for some time are still going strong in animal populations – specifically, in the white-tailed deer (Odocoileus virginianus) roaming across the state of New York in the...

What's more, the viral sequences recovered from the deer show substantial genetic changes from the ones carried by humans, suggesting that SARS-CoV-2, the virus that causesBased on the time that the samples were gathered, it seems likely that the virus is able to circulate in deer for months after its last detection in people. It's possible that these animals are acting as long-term reservoirs for SARS-CoV-2 variants.

"One of the most striking findings of this study was the detection of co-circulation of three variants of concern – Alpha, Gamma, and Delta – in this wild animal population,"The study was based on 5,462 existing samples of deer lymph tissue, collected as part of an investigation into chronic wasting disease in white-tailed deer. These samples were gathered across 2020 and 2021, and with useful data attached about when and where they were collected, plus the age and sex of each deer.

All of that data meant the researchers were able to identify hotspots where SARS-CoV-2 was particularly active. Multiple clusters were shown to exist based exclusively around particular variants: Alpha, Gamma, or Delta. The team was also able to identify as many as 80 mutations in some of the virus variants, indicating that this wasn't a short-term visit. These mutations potentially make it easier for SARS-CoV-2 to pass to other animals, and perhaps even back to humans.

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