Even stronger obesity drug could further upend weight-loss care

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Even stronger obesity drug could further upend weight-loss care
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As a growing number of overweight Americans clamor for Ozempic and Wegovy — drugs touted by celebrities and on TikTok to pare pounds — an even more powerful obesity medicine is poised to upend treatment.

— drugs touted by celebrities and on TikTok to pare pounds — an even more powerful obesity medicine is poised to upend treatment.

"If everybody who had obesity in this country lost 20% of their body weight, we would be taking patients off all of these medications for reflux, for diabetes, for hypertension," said Dr. Caroline Apovian, a director of the Center for Weight Management and Wellness at Brigham and Women's Hospital."We would not be sending patients for stent replacement."

"Psychologically, you don't want to eat," said Barlow."Now I can eat two bites of a dessert and be satisfied." The obesity medications help overcome a biological mechanism that kicks in when people diet, triggering a coordinated effort by the body to prevent weight loss."That is a real physical phenomenon," Aronne said."There are a number of hormones that respond to reduced calorie intake."

Though the drugs appear safe, they can cause side effects, some serious. Most common reactions include diarrhea, nausea, vomiting, constipation and stomach pain. Some users have developed pancreatitis or inflammation of the pancreas, others have had gallbladder problems. Mounjaro's product description warns that it could cause thyroid tumors, including cancer.

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