Drs Peter Martin and Eric Hsi have a thought-provoking discussion on key topics in the pathology of mantle cell lymphoma, including biopsies, diagnostic markers, and what the future holds for treatment. WCMLymphoma MCL
that helped to find what the incidence is. They took over 1000 all-comer reactive lymph node biopsies and then went back and just stained them all and found no cases. We don't do that. We don't go looking in all the sample lymph nodes for in situ mantle cell lymphoma by immunostaining when you're really looking for metastatic disease, which you can just do on a hematoxylin and eosin — H&E — without doing any kind of extra staining.
platforms can give you that answer. But those are not clinical instruments. There may be somebody running that clinically, but I'm not aware of anyone doing it.running the basic science side of a mantle cell lymphoma program, and finding, interestingly, that the mutational burden of mantle cell lymphomas early on really is not that impressive. It really seems like copy number alterations are going to be a lot more relevant in the future.
, and listen and subscribe to this podcast series on mantle cell lymphoma. This is Dr Peter Martin for
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