Did the diagnosis and management of Hodgkin lymphoma differ during the SARS-CoV-2 pandemic? HodgkinLymphoma Lymphoma Pandemic COVID19 SARSCoV2
By Pooja Toshniwal PahariaOct 17 2022Reviewed by Aimee Molineux In a recent study published in Current Problems in Cancer, researchers evaluated the impact of the severe acute respiratory syndrome coronavirus 2 pandemic on the diagnosis and treatment of classical Hodgkin lymphoma patients in Istanbul, Turkey.
About the study In the present retrospective and single-center cohort study, researchers compared the symptom-to-diagnosis interval , the diagnosis-to-treatment interval , stages of cHL, and chemotherapy responses among individuals, diagnosed and managed for cHL in the pandemic and pre-pandemic-periods.
Related StoriesAll cHL patients received ≥1 chemotherapy dose, with bleomycin, brentuximab vedotin , doxorubicin-vinblastine-dacarbazine , or anthracycline. PFTs such as DCLO and spirometry, and positron emission tomography-computed tomography were evaluated intermittently and after every two treatment cycles.
Early-stage and advanced-stage cHL was present among 43% and 57% of the participants, respectively. Extranodal involvement was identified in 49% of cases, and the EN sites most frequently involved were the spleen, lungs, liver, and bone in 38%, 11%, 10%, and eight percent of cases, respectively. Bone marrow was involved in four percent of cases.
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