New WHO guidance declared there is no proof that the presence of antibodies means a patient cannot be infected with the new coronavirus again -- so where does that leave antibody testing as a weapon against COVID-19?
“People infected by any one of these viruses may produce antibodies that cross-react with antibodies produced in response to infection with SARS-CoV-2,” the WHO says.Progress Made in Analysis
At Duke, Thomas Denny is a professor of medicine and chief operating officer at the Duke Human Vaccine Institute. The test they’re using is part of a research study to find out if a positive antibody test means future protection. “We hope that one would develop an antibody response that would confirm protection as we’ve seen with other infectious diseases, but until we have the data that proves that we don’t know for certain, and I think we need to be a bit cautious in where we’re going with all of it until we have the data that confirms it,” he says.
Still, he said, widespread antibody testing “will help us track the spread of the virus nationwide and assess the impact of our public health efforts now, while also informing our COVID-19 response as we continue to move forward.” But, Hahn said, they won’t object if developers market or use their tests without prior FDA review as long as they follow three rules: The developer validates it has determined the tests are accurate and reliable, the developer notifies the FDA of its own validation, and the tests are labeled appropriately, including that they are not to be used as a sole basis for diagnosis.
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