Several studies provide evidence that a stimulant medication can improve executive functions in menopausal women without ADHD who report decline in working memory, organization, focus and attention that was not experienced prior to menopause.
or with placebo, followed by a four-week washout period and a six-week trial of whichever of those two treatments they had not previously been given.
The second study in this series involved 32 healthy women aged 45 to 60 who reported mid-life onset of executive function symptoms as measured by the BADDS. All of the women were required to have had irregular menstrual cycles for at least the previous 12 months and no menstrual period for at least 3 months. None had a history of ADHD.
Participants in that third study were 14 women aged 45 to 60 who reported executive function difficulty that had started during menopause. All were within 5 years of their last menstrual period. Each was tested with the BADDS scale at starting point and after a 4-week trial of LDX and a 4-week trial of placebo, during which researchers and the women were all blinded as to who was on medication or placebo.
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