NFL predictions, picks, and odds for Indianapolis Colts vs Jacksonville Jaguars. NFL Week 6 betting best bet and game analysis.
Jacksonville has already gotten the best of Indianapolis once this season, and history over the years shows Trevor Lawrence & Co. should be in for more success against the Horsehoe in Week 6. Read more in our Colts vs. Jaguars betting picks.. The Jaguars are returning home after a two-week stint in London and now square up against a Colts side that will be missing starting quarterback Anthony Richardson.
However, this is an offense that is finally starting to click after underperforming earlier this season. While the Jags offense ranked just 29th in the league in EPA after Week 3, they are eighth in EPA over the last two weeks. Meanwhile, Moss is coming off a monster 165-yard game but he's due for regression against a Jags stop unit that ranks fourth in defensive rush EPA and limits foes to 3.7 yards per carry. We also need to factor in that Taylor is back in the lineup and vying for more snaps after coming off an injury to make his season debut last week.The spread has slimmed from Jaguars -5 to -4 while the total has ticked down from 45.5 to 44.5.
After that victory, the Jags dropped back-to-back games against the Chiefs and Texans but they got back on track in London, beating the Falcons in Week 4 before upsetting the Bills as 5.5-point pups last week.
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