Chargers vs 49ers Odds, Picks & Predictions

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Chargers vs 49ers Odds, Picks & Predictions
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NFL odds, picks and predictions for Los Angeles Chargers vs San Francisco 49ers. NFL preseason betting best bet and game analysis.

That trio has combined to throw for 496 yards with three touchdowns and two picks this preseason while leading a combined five scoring drives.

The Shanahan family’s bread and butter has always been running the football, and the 49ers will surely lean on their ground game . Outside of some strong reps from third-year undrafted offensive tackle Foster Sarell and fifth-round rookie Jordan McFadden, the Chargers backup offensive line room shouldn’t inspire much confidence.

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