Can you shed infectious SARS-CoV-2 virions even if COVID vaccinated? SARSCoV2 Coronavirus Disease COVID ViralShedding Virology UWMadison CDCgov PLOSPathogens
Study: Shedding of infectious SARS-CoV-2 despite vaccination. Image Credit: MrSquid / Shutterstock
About the study In the present study, researchers evaluated the SARS-CoV-2 ribonucleic acid burden in nasal swabs obtained from vaccinated and unvaccinated people to ascertain if people with vaccine breakthrough infections might shed SARS-CoV-2 Delta viruses at levels compatible with the potential transmission.
If vaccine registry or self-reported data showed that a final vaccine dosage was received at least 14 days before the submission of a SARS-CoV-2 positive, the individual was deemed completely vaccinated at the time of testing. The team evaluated the presence of an infectious virus and observed the presence of cytopathic effects throughout the course of five days using an initial batch of specimens with Ct values less than 25.
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