A study published in BMCMedicine finds that greater number of chronic pain sites is associated with an increased risk of all-cause dementia and Alzheimer’s disease and may be an accessible marker to assess dementia risk at early stages.
]. Thus, it remains unclear whether the excess risk is attributable to these potential confounding factors.
Currently, there is no study exploring the associations between chronic pain in multiple sites and risk of incident dementia as well as its subtypes.
]. The UK Biobank study was approved by the North West Multi-centre Research Ethics Committee, and all participants provided electronic informed consent. The current analyses were restricted to participants without self-reported or prevalent dementia at baseline.Participants were asked at baseline whether they had experienced pain at the sites of the hip, knee, back, and neck/shoulder in the last month that interfered with their usual activities.
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