Research published in the European Journal of Medical Research presents a case series of eight patients with cardiac adverse events like myocarditis or pericarditis shortly after SARS-CoV-2 mRNA vaccination.
Widening of the QRS complex in all ECG leads, and ST-Elevations in I, II, III, aVF and inverted in aVR.Transient widening of the QRS complex has receded. There is left only a mild preterminal T negativity in lead IIIA 28-year-old male presented in the emergency Department 2 days after the second dose vaccination with mRNA1273, Spikevax© with acute chest pain and ST-elevation mimicking ST elevation myocardial infarction .
Because of the muscular dystrophy, cardiac enzymes were differentiated into Troponin I and Troponin T . A cardiac magnetic resonance imaging was performed on day 4 revealing signs of mild myocarditis with edema and elevated T2-relaxation-times. Echocardiography showed decreased strain function which normalized within the next 2 days.After 5 days in the intermediate care unit, the patient was discharged without any residual symptoms.
Myocarditis is a rare post-vaccination side effect, recently observed 1–5 days after the administration of mRNA-based COVID-19 vaccines, such as BNT126b2 or mRNA-1273. The onset and the symptomatology are consistent with the data reported by Diaz et al. in JAMA [
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