New wearable sensor detects even more compounds in humansweat Caltech natBME
. Selected ion monitoring was used, which records the ion current at selected masses that are characteristic of the certain AA in an expected retention time. For example, after the derivatization of the EZ:Faast kit, Trp has a characteristic mass at 130 with a retention time at around 5.1 min, and peak height is recorded for Trp measurements at ion number 130 and at 5.1 min from the raw data spectrum.
Sweat samples were collected periodically from the subjects during the studies using centrifuge tubes. The sweat samples were then frozen at −20 °C for further testing and validation via electrochemical test with the biosensors and GC–MS analysis.The subjects reported to the lab after fasting overnight. The subjects’ arms were cleaned with alcohol swabs and gauze before the sensor patches were placed on the body. The subjects were provided Tyr and Trp supplement for the intake study.
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