Asthma is thought to affect more than 250 million people worldwide and is responsible for hundreds of thousands of deaths each year.
. Most often found in the lining of blood vessels, pericytes are known to thicken the airways of people with asthma when an allergic and inflammatory reaction happens, making breathing more difficult.
Stopping pericytes from traveling to the airway walls – where they turn into muscle cells and other cells that make the airway thicker and more rigid – would impact one of the underlying causes of shortness of breath.
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